03/10/2023: Our lab has received a new R01 grant from NIEHS. The grant aims to investigate the role of RNA binding proteins in xenobiotic-induced Hepatocellular Carcinoma. Many thanks to our collaborators and the NIEHS.
03/08/2023: Dr. Ishita Choudhary has received Health and Environmental Sciences Institute (HESI) Immuno-Safety Technical Committee (ITC) Professional Development Award. Congratulations!
03/06/2023: Ishita Choudhary successfully defensed her PhD dissertation. Congratulations Dr. (DVM) Dr. (PhD) Choudhary. As a consequence, Saini Lab has graduated its second PhD student.
03/04/2023: Ishita Choudhary has Women in Toxicology Vera W. Hudson and Elizabeth K. Weisburger Scholarship Fund Award. Congratulations!
03/01/2023: Ishita Choudhary has received prestigious 2023 Roger O McClellan award. Congratulations!
01/06/2023: Our lab has received $ 403,318 funding as a new R21 grant from NIEHS. The grant aims to investigate the molecular and cellular pathways of mucous cell metaplasia in ozone-exposed airways. Many thanks to the NIEHS.
12/30/2022: Saini Lab published their paper entitled “Mafb promoter activity may define the alveolar macrophage dichotomy” in Frontiers in Immunology. Congratulations to all the authors!
12/20/2022: Saini Lab published their paper entitled “Induction of whole-body gene deletion via R26-regulated tamoxifen-inducible Cre recombinase activity“ in Frontiers in Pharmacology. Congratulations to all the authors!
12/10/2022: Thao received Heidi Lott Award for her outstanding performance in her graduate studies.
11/01/2022: Saini Lab published their paper entitled “Higher susceptibility of males to bleomycin-induced pulmonary inflammation is associated with sex-specific transcriptomic differences in myeloid cells“ in Toxicology and Applied Pharmacology. Congratulations to all the authors!
09/12/2022: Saini Lab published their paper entitled “Silencing of RNA binding protein, ZFP36L1, promotes epithelial-mesenchymal transition in liver cancer cells by regulating transcription factor ZEB2“ in Cellular Signalling. Congratulations to all the authors!
08/30/2022: Saini Lab published their paper entitled “In Vitro Screening Method for Characterization of Macrophage Activation Responses“ in Methods and Protocols. Congratulations to all the authors!
08/01/2022: Thao Vo received a travel grant to attend the SETAC North America 43rd Annual Meeting that is taking place in Pittsburgh. Congratulations!
04/22/2022: Ishita Choudhary received the Society of Toxicologic Pathology (STP) Student “Travel Grant” award for the STP 41st Annual Symposium that is taking place in Austin, Texas (June 19–23, 2022). Congratulations!
03/15/2022: Our Lab received the “Paper of the Year Award” at the 2022 Society of Toxicology (SOT) Annual Meeting in San Diego, March 27 – 31, 2022. This paper entitled “Postnatal ozone exposure disrupts alveolar development, exaggerates muco-inflammatory responses, and suppresses bacterial clearance in developing Scnn1b-Tg+ mice lungs“ was published in The Journal of Immunology.
02/23/2022: Dhruthi Singamsetty received “First Place” presentation awards for her presentation at the 2022 Phi Zeta Research Day. Congratulations!
02/23/2022: Ishita Choudhary received the “Fourth Place” presentation award for her presentation at the 2022 Phi Zeta Research Day. Congratulations!
01/12/2022: Thao Vo received the best presentation award (First Place) at the annual departmental retreat.
01/12/2022: Ishita Choudhary received the best presentation award (Second Place) at the annual departmental retreat.
01/01/2022: Saini Lab published their paper entitled “Ozone exposure upregulates the expression of host susceptibility protein TMPRSS2 to SARS-CoV-2” in Scientific Reports. Congratulations to all the authors!
12/01/2021: Saini Lab published their paper entitled “Vesicular and extravesicular protein analyses from the airspaces of ozone-exposed mice revealed signatures associated with mucoinflammatory lung disease” in Scientific Reports. Congratulations to all the authors!
07/16/2021: Saini Lab published their paper entitled “Myeloid IL-4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Ra axis of eosinophil recruitment in murine lungs” in Scientific Reports. Congratulations to all the authors!
06/24/2021: Ishita Choudhary received “Young Investigator Award” at 2021 annual Society of Toxicologic Pathology (STP) meeting. Congratulations!
06/04/2021: Ishita Choudhary is the recipient of “2021 Society of Toxicologic Pathology (STP) Environmental Toxicologic Pathology Special Interest Group (ETP-SIG) Student Research Award“. Congratulations!
06/03/2021: Saini Lab published their paper entitled “Postnatal ozone exposure disrupts alveolar development, exaggerates mucoinflammatory responses, and suppresses bacterial clearance in developing Scnn1b-Tg+ mice lungs“ in The Journal of Immunology. Congratulations to Ishita Choudhary (first author) and all the co-authors!
05/01/2021: Received INBRE/COBRE Collaborative Project funding from NIGMS to study the “Protective Role of Activating Transcription Factor 6 (ATF6) against endothelial barrier dysfunction”. The proposal is a collaborative effort between our laboratory and Nektarios Barabutis laboratory at the University of Louisiana at Monroe.
04/17/2021: Ishita Choudhary received “First Place” presentation awards on her presentation at the 8th Annual Louisiana Biomedical Research Network Conference on Computational Biology and Bioinformatics (April 15 – 17, 2021). Congratulations!
04/09/2021: Dr. Saini received Distinguished Research Scholar Award.
03/15/2021: Ishita Choudhary presented her research at the 2021 Comparative Toxicology, Pathology, and Veterinary Specialty Section (CTPVSS) meeting.
02/26/2021: Ishita Choudhary is the recipient of the 2021 Comparative Toxicology, Pathology, and Veterinary Specialty Section (CTPVSS) Trainee Award. She will receive a plaque and monetary award to attend the meeting. Congratulations!
02/24/2021: Kshitiz Paudel received “First Place” presentation awards on his presentation at the 2021 Phi Zeta Research Day. Congratulations!
02/24/2021: Thao Vo received “Third Place” presentation awards on her presentation at the 2021 Phi Zeta Research Day. Congratulations!
02/24/2021: Ishita Choudhary received “First Place” presentation awards on her presentation at the 2021 Phi Zeta Research Day. Congratulations!
02/24/2021: Ishita Choudhary received “Second Place” presentation awards on her presentation at the 2021 Phi Zeta Research Day. Congratulations!
01/12/2021: Dhruthi Singamsetty received the best presentation award (Second Place) at the annual departmental retreat.
01/12/2021: Ishita received Heidi Lott Award for her outstanding performance in her graduate studies.
01/12/2021: Thao Vo received the best presentation award (First Place) at the annual departmental retreat.
11/13/2020: Ishita presented a platform talk at the Annual South-central Chapter of SOT Meeting (13th November, 2020). She shared her recent findings from her project entitled “Effect of ozone on the progression of CF-like lung disease in mice“.
10/05/2020: Saini Lab published their paper entitled “Compartment-specific transcriptomics of ozone-exposed murine lungs reveals sex and cell type-associated perturbations relevant to mucoinflammatory lung diseases” in The American Journal of Physiology Lung Cellular and Molecular Physiology. Congratulations to the Authors!
07/21/2020: Saini Lab published their paper entitled “Innate lymphoid system is a critical player in the manifestation of muco-inflammatory airway disease in mice” in The Journal of Immunology. Congratulations to the Authors!
04/27/2020: Saini Lab published their paper entitled “Lung macrophages: Current understanding of their roles in ozone-induced lung diseases” in Critical Reviews in Toxicology.
02/12/2020: Ishita Choudhary received “First Place” presentation awards on her presentation at the 2020 Phi Zeta Research Day. Congratulations!
02/06/2020: Saini Lab welcomes new graduate student, Dhruthi Singamshetty.
01/15/2020: Saini Lab published their paper entitled “Ablation of IL33 suppresses Th2 responses, but with sustained mucus obstruction, in the Scnn1b transgenic mouse model” in The Journal of Immunology. Congratulations to the major authors: Brandon, Taylor, and Ishita!
01/14/2020: Radha Yadav (Postdoctoral Fellow) received the best presentation award at the annual departmental retreat.
01/01/2020: Dr. Saini got early tenure and promotion to Associate Professor.
08/25/2019: Saini Lab welcomes new graduate student, Yun Mao.
08/15/2019: Saini Lab welcomes new graduate student, Kshitiz Ranzan Paudel.
06/17/2019: Saini Lab welcomes new postdoctoral fellow, Radha Yadav.
06/10/2019: Saini Lab welcomes new graduate student, Ishita Choudhary.
05/27/2019: Saini Lab published their paper entitled “Immunopathology of Airway Surface Liquid dehydration disease” in The Journal of Immunology Research.
04/29/2019: Dr. Saini received 2019 LSU Alumni Association Rising Faculty Research Award at the University Distinguished Faculty Award Ceremony.
03/20/2019: Dr. Saini received 2019 Zoetis Award for Veterinary Research Excellence.
01/31/2019: Brandon Lewis, the first graduate student of the lab, successfully defended his Ph.D. dissertation and turned into Dr. Brandon Lewis. Congratulations! Dr. Lewis.
01/31/2019: Dr. Saini received Outstanding New Environmental Scientist (ONES) Award from NIEHS.
01/31/2019: Our lab received $2.7 Million R01 grant (2019-2024) from NIEHS to investigate the roles of myeloid cells in ozone-induced lung diseases.
01/08/2019: Our lab received federal funding ($259,000/year) from NIGMS. This award is a component of the recent Center of Biomedical Research Excellence (COBRE) grant to the School of Veterinary Medicine at Louisiana State University.
11/28/2018: Thao Vo (Taylor) joined the group as graduate student. Welcome, Taylor!!
08/18/2018: Allison Kidder joined the group as undergraduate researcher. Welcome, Allison!!
06/24/2018: Our lab received $147,000 research funding from the Louisiana Board of Regents. Our proposal was ranked 1st (tied with 14 other proposals) in a total of 151 proposals that were submitted statewide in the year 2017.
05/15/2018: Saini Lab published their abstract entitled “Ablation of adaptive immune responses facilitates bacterial clearance in murine model of defective muco-ciliary clearance” in the Journal of Immunology.
05/01/2018: Manuscript entitled “Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis” was selected as Editor’s Choice in Physiological Reports.
04/20/2018: Our lab received $50,000 pilot project research funding from the Center for Experimental Infectious Diseases and Research (CEIDR). This award was supported by NIGMS Parent Award 5P30GM110760.
04/30/2018: Saini Lab published their paper entitled “Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis” in Physiological Reports.
03/20/2018: Our Lab received Paper of the Year award at the 2018 Society of Toxicology (SOT) Annual Meeting in San Antonio, March 11 – 15, 2018.
03/18/2018: Dr. Saini received AAI early career award.
01/08/2018: Brandon Lewis received a presentation award at the annual CBS retreat.
07/25/2017: Presented at summer seminar series conducted by Louisiana Biomedical Research Network.
07/24/2017: Our Journal of Immunology paper is highlighted in the journal’s issue.
06/05/2017: Saini Lab published their paper entitled “Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease” in the Journal of Immunology.
03/18/2017: Brandon Lewis received Toxicologic and Exploratory Pathology Charles River Award, Society of Toxicology Graduate Student Award, Comparative and Veterinary Student awards at Society of Toxicology Meeting in Baltimore.
02/16/2017: Saini Lab presented at Gordon Research Conference.
01/08/2017: Owias Mohammad (Postdoctoral Fellow) received a presentation award at the annual CBS retreat.
05/20/2016: Our lab received $50,000 pilot project research funding from the Center for Experimental Infectious Diseases and Research (CEIDR). This award was supported by NIGMS Parent Award 5P30GM110760.
03/18/2016: Dr. Saini received AAI early career award.
05/18/2015: Dr. Saini received first place presentation award at FAMRI symposium.
05/18/2015: Dr. Saini presented an invited talk at FAMRI symposium.
06/18/2015: Saini Lab published their paper entitled “Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses” in the American Journal of Respiratory Cell and Molecular Biology.
06/30/2015: Our lab received $217,000 funding from the Flight Attendant Medical Research Institute (FAMRI) for a period of two years.
06/30/2015: Saini lab received $10,000 pilot project funding from SVM Competitive Organized Research Program (CORP) at Louisiana State University.
01/10/2015: Presented at CBS annual retreat.
01/01/2015: Brandon Lewis, a CBS graduate student, joined the lab.
10/15/2014: Laboratory was established at LSU!
The Saini Lab 