Publications

Yogesh Saini*, Brandon Lewis, Kristen Wilkinson, Hong Dang, Alessandra Livraghi-Butrico, Wanda K O’Neal, Richard C Boucher. Pulmonary macrophage depletion alters the lung pathology associated with defective mucus clearance. (Accepted for publication in Physiological reports; February 2018). (*Corresponding Author).

Dongfang Yu, Yogesh Saini, Gang Chen, Ghio AJ, Hong Dang, Kimberly A. Burns, Yang Wang, RM Davis, Scott H Randell, Charles R Esther Jr, Fredrick Paulsen, Richard C Boucher. Loss of β Epithelial Sodium Channel Function in Meibomian Glands Produces Pseudohypoaldosteronism 1-Like Ocular Disease in Mice. American Journal of Pathology 2018 Jan;188(1):95-110.

Brandon W Lewis, Razia, Sultana, Rahul Sharma, Alexandra Noël, Ingeborg Langohr , Sonika Patial, Arthur L Penn,Yogesh Saini. Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease. Journal of Immunology 2017 Aug 1;199(3):1170-1183. (Journal’s Issue Highlight)

Yogesh Saini, Steven P. Proper, Peter Dornbos, Krista K Greenwood, Anna K Kopec, Scott G Lynn, Elizabeth Grier, Lyle D Burgoon, Timothy R Zacharewski, Russell S Thomas, Jack R Harkema, John J LaPres. Loss of HIF2α rescues the HIF1α deletion phenotype of neonatal respiratory distress in mice. PLoS One. 2015 Sep 30;10(9):e0139270.

    Yogesh Saini*, Kristen Wilkinson, Kristy Terrell, Kimberlie A Burns, Alessandra Livraghi-Butrico, Claire M Doerschuck, Wanda K O’Neal, Richard C Boucher. Neonatal pulmonary macrophage depletion coupled to defective mucus clearance alters pulmonary immune responses. American Journal of Respiratory Cell and Molecular Biology 2016 Feb;54(2):210-21. (*Corresponding Author).

    Anand R Nair, Philip J Ebenezer, Yogesh Saini, Joseph Francis. Angiotensin II-induced hypertensive renal inflammation is mediated through HMGB1-TLR4 signaling in rat tubulo-epithelial cells. Exp Cell Res. 2015 Jul 15;335 (2):238-47.

    Hyejin Hwang, Scott G Lynn, Ajith Vengellur, Yogesh Saini, EA Grier, SM Fergusan-Miller, John J LaPres. Hypoxia Inducible Factors (HIFs) modulate mitochondrial oxygen consumption and transcriptional regulation of nuclear encoded electron transport chain genes. Biochemistry. 2015 Jun 23;54(24):3739-48.

    Yogesh Saini*, Hong Dang, Alessandra Livraghi-Butrico, E. Kelly, Lisa Jones, Wanda K O’Neal, Richard C Boucher. Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration. BMC Genomics 2014; 15:726. (*Corresponding Author).

    Steven P Proper*, Yogesh Saini*, Krista K Greenwood, Lori A Bramble, Nathaniel J Downing, Jack R Harkema, John J LaPres. Loss of hypoxia-inducible factor 2 alpha (HIF2α) in the lung alveolar epithelium of mice leads to enhanced eosinophilic inflammation in cobalt-induced lung injury. Toxicological sciences, 2014 February; 137(2):447-57. (*Equal Contribution)

    Krista K Greenwood, Steven P Proper, Yogesh Saini, Daven N Jackson-Humbles, Jim G Wagner, Lori Bramble, Jack R Harkema, John J LaPres. Neonatal epithelial hypoxia inducible factor-1α expression regulates the lung’s response to experimental asthma. Am J Physiol Lung Cell Mol Physiol.2012 March; 302(5):L455-462.

    Erica M Sparkenbaugh, Yogesh Saini, John J LaPres, Jane Maddox, PE Ganey and Robert A Roth. The role of hypoxia inducible factor-1 alpha (HIF-1α) in acetaminophen J Pharmacol Exp Ther. 2011 August; 338(2):492-502.

    Sonika Patial, Shipra Shahi, Yogesh Saini, Daniel M Appledorn, John J LaPres, Andrea Amalfitano and Narayanan Parameswaran. G-protein coupled receptor kinase 5 (GRK5) regulates LPS induced NFκB pathway and is necessary for the production of pro-inflammatory cytokines and chemokines in LPS induced septic shock model of mice. Journal of Cellular Physiology, 2011 May; 226 (5):1323-33.

    Sonika Patial, Yogesh Saini, Daniel M Appledorn, Gerald W Dorn, John J LaPres, Andrea Amalfitano, Patricia Senagore and Narayanan Parameswaran. Myeloid-specific GPCR kinase-2 negatively regulates NFκB1p105-ERK pathway and limits endotoxemic shock in mice. Journal of Cellular Physiology, 2011 March; 226 (3):627-37.

    Yogesh Saini, Krista K Greenwood, Christian Merrill, Kyung Y Kim, Sonika Patial, Jack R Harkema, John J LaPres. Acute Cobalt-Induced Lung Injury and the Role of Hypoxia Inducible Factor 1α (HIF1α) in Modulating Inflammation.Toxicological sciences, 2010 August; 116 (2): 673-681.

    Yogesh Saini, Kyung Y Kim, Lori Bramble, Ryan Lewandowski, Jack R Harkema, John J LaPres. Role of Hypoxia Inducible Factor 1 alpha (HIF1α) in cobalt-induced lung injury. Am J Physiol Lung Cell Mol Physiol.2010 February; 298(2):L139-47.

    Yogesh Saini, Jack R Harkema, John J HIF1α is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice. Journal of Biological Chemistry, 2008 November; 28; 283(48):33650-33657.

    Sonika Patial, VK Chaturvedi, A Rai, M Saini, Rajesh Chandra, Yogesh Saini and Praveen K Gupta. Virus neutralizing antibody response in mice and dogs with a bicistronic DNA vaccine encoding rabies virus glycoprotein and canine parvovirus VP2. Vaccine, 2007 May; 25:4020-4028.

    Thakur SD, Vaid RK, Panda AK and Yogesh Saini. Marine mammal brucellosis: a new dimension to an old zoonosis. Current Science, 2012 October; 103(8):902-910.

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